Synthesis of substituted 1,2,3-triazoles via N-sulfonylaziridines

Abstract

Nucleophilic ring-opening of N-sulfonylaziridines by sodium azide leads to β-azidoamines. The regioselectivity of this reaction and new efficient catalyst for such 1,3-dipolar cycloaddition are reported. Several 1,2,3-triazoles have been synthesized and their structures established by X-ray crystallography, MS, IR and 1H NMR spectral data. © ARKAT.