Chimeric Ply187 endolysin kills Staphylococcus aureus more effectively than the parental enzyme

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Abstract

Peptidoglycan hydrolases are an effective new source of antimicrobials. A chimeric fusion protein of the Ply187 endopeptidase domain and LysK SH3b cell wall-binding domain is a potent agent against Staphylococcus aureus in four functional assays. © 2013 Federation of European Microbiological Societies.

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Mao, J., Schmelcher, M., Harty, W. J., Foster-Frey, J., & Donovan, D. M. (2013). Chimeric Ply187 endolysin kills Staphylococcus aureus more effectively than the parental enzyme. FEMS Microbiology Letters, 342(1), 30–36. https://doi.org/10.1111/1574-6968.12104

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