Infantile osteopetrosis; bone marrow transplantation from a cousin donor

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Abstract

The successful correction of infintile osteopetrosis in an Asian child by bone marrow transplantation (BMT) from an HLA-A,B matched cousin donor is reported. Retrospective HLA molecular analysis revealed that patient and donor were incompatible for HLA-DPB1. Donor type cells detected in the patient after transplantation indicate successful engraftment. The patient is currently alive and well.

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Taylor, G. M., Dearden, S. P., Will, A. M., Evans, D. I. K., Stevens, R. F., Simon, S., … Brown, I. H. (1995). Infantile osteopetrosis; bone marrow transplantation from a cousin donor. Archives of Disease in Childhood, 73(5), 453–455. https://doi.org/10.1136/adc.73.5.453

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