6-Benzyl-3,4-dimeth-oxy-10-methyl-pyrido[2′,1′:2,3]imidazo[4, 5-c]isoquinolin-5(6H)-one

Abstract

Pyrido[2′,1′:2,3]imidazo[4,5-c]isoquinolin-5(6H)-ones such as the title compound, C24H81N3O3, can be obtained in a few minutes in a microwave-assisted three-component reaction from 2-amino-pyridines, isocyanides and 2-carboxy-benz-aldehydes. In the title compound, the pyrido[2′,1′:2,3]imidazo[4,5-c]isoquinolin-5(6H)-one ring system is almost planar (mean deviation 0.068 Å). The dihedral angle between the benzyl ring and the pyrido[2′,1′:2,3]imidazo[4,5-c] isoquinolin-5(6H)-one ring system is 78.2°. The crystal structure is stabilized by inter-molecular C- H⋯O and C- H⋯N hydrogen bonds.