Leber's hereditary optic neuropathy (LHON/11778) with myoclonus: Report of two cases

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Abstract

The previously unrecognised association of myoclonus in two patients with LHON with the 11778/ND4 pathogenic mutation is described. EEG failed to disclose epileptic figures, and a back averaging study suggested that myoclonus was cortical in origin in both patients.

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Carelli, V., Valentino, M. L., Liguori, R., Meletti, S., Vetrugno, R., Provini, F., … Montagna, P. (2001). Leber’s hereditary optic neuropathy (LHON/11778) with myoclonus: Report of two cases. Journal of Neurology Neurosurgery and Psychiatry, 71(6), 813–816. https://doi.org/10.1136/jnnp.71.6.813

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