Abstract
A two step synthesis of 2-alkynyl-4-arylquinolines has been accomplished via Pd/C-mediated regioselective C-2 alkynylation of 2,4-dichloroquinoline in water followed by Suzuki coupling at C-4 of the resulting 4-chloro derivative. © 2009 Reddy et al; licensee Beilstein-Institut.
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Reddy, E. A., Islam, A., Mukkanti, K., Bandameedi, V., Bhowmik, D. R., & Pal, M. (2009). Regioselective alkynylation followed by Suzuki coupling of 2,4-dichloroquinoline: Synthesis of 2-alkynyl-4-arylquinolines. Beilstein Journal of Organic Chemistry, 5. https://doi.org/10.3762/bjoc.5.32
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