Journal ArticleOPEN ACCESS

Metabolic and transcriptional profiling reveals pyruvate dehydrogenase kinase 4 as a mediator of epithelial-mesenchymal transition and drug resistance in tumor cells

  • Sun Y
  • Daemen A
  • Hatzivassiliou G
  • et al.
Cancer & Metabolism (2014) 2(1)
DOI: 10.1186/2049-3002-2-20
N/ACitations
Citations of this article
148Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Background: Accumulating preclinical and clinical evidence implicates epithelial-mesenchymal transition (EMT) in acquired resistance to anticancer drugs; however, mechanisms by which the mesenchymal state determines drug resistance remain unknown.

Cite

CITATION STYLE

APA

Sun, Y., Daemen, A., Hatzivassiliou, G., Arnott, D., Wilson, C., Zhuang, G., … Settleman, J. (2014). Metabolic and transcriptional profiling reveals pyruvate dehydrogenase kinase 4 as a mediator of epithelial-mesenchymal transition and drug resistance in tumor cells. Cancer & Metabolism, 2(1). https://doi.org/10.1186/2049-3002-2-20

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free