Diagnosis of genetic diseases by dna technology

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Abstract

The development of recombinant DNA technology has allowed the study of the molecular pathology of inherited diseases in man. Two main molecular approaches are employed: direct study for detection of molecular defects and indirect detection by linkage analysis, A variety of new technologies and their applications have provided a powerful new tool in the diagnosis of inherited diseases. © 1991 IUPAC

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Ferrari, M., Cremonesi, L., Carrera, P., & Bonini, P. (1991). Diagnosis of genetic diseases by dna technology. Pure and Applied Chemistry, 63(8), 1089–1096. https://doi.org/10.1351/pac199163081089

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