Salivary stimulation-could it play a role in GERD management?

Abstract

Multiple diverse studies indicate that swallowed saliva plays an important role in neutralizing stomach acid refluxed into the esophagus and mouth; the acid that causes the symptoms of gastro-esophageal reflux disease (GERD). This article briefly reviews the epidemiology of GERD, its pathogenesis and symptom presentation, its connection to salivation, and its medical management and presents results from a study suggesting that an increase in salivation during sleep can significantly improve symptoms associated with the condition. The presented study demonstrates that an OTC product currently on the market (OraCoat XyliMelts) that is specifically designed to increase salivation through the slow release of flavoring is an effective adjunctive remedy for reducing reflux and heartburn symptoms associated with sleep related GERD.