Nanofocused synchrotron X-ray absorption studies of the intracellular redox state of an organometallic complex in cancer cells

Abstract

Synchrotron nanoprobe X-ray absorption (XAS) studies of a potent organo-osmium arene anticancer complex in ovarian cancer cells at subcellular resolution allow detection and quantification of both OsII and OsIII species, which are distributed heterogeneously in different areas of the cells.