Acute ventilatory changes during I.V. Induction of anaesthesia with thiopentone or propofol in man: Studies using inductance plethysmography

Abstract

We have compared the acute ventilatory changes during induction of anaesthesia with equipotent doses of thiopentone and propofol in 12 premedicated female patients. Using ventilatory inductance plethysmography we have shown that both agents depress respiration to a similar and significant degree (P < 0.001). However, although the functional residual capacity was reduced in patients receiving propofol, it increased slightly after induction with thiopentone (P <0.05). © 1987 Copyright: 1987 British Journal of Anaesthesia.