Synthesis of hierarchically porous bioactive glasses using natural plants as template for bone tissue regeneration

Abstract

A series of highly ordered hierarchically porous silica and bio-glasses materials with macropore size of 8-1,000 μm and mesopore size of 3.1-5.6 nm have been synthesized using six plant based materials as templates. However, the as-obtained porous structure was reported for the first time with interconnected 3D macropore up to 1,000 μm. The porous silica materials were used as the host for drug loading and release, which showed a good sustained delivery function. The as-synthesized bio-glasses materials indicated the highly bioactive capability in the bone regeneration. This method can be utilized to synthesize other multi-porous bioactive glasses using different plants as templates for bone tissue repairing. © Springer Science+Business Media, LLC 2012.