Healing and Prophylactic Effects of Moringa oleifera Leaf Extract on Lead Induced Damage to Haematological and Bone Marrow Elements in Adult Wistar Rat Models

Abstract

TThis study was carried out to observe the regenerative effect of Moringa oleifera extract on Hematological Parameters and Bone Marrow of adult Wistar Rat, using thirty five (35) Rats which were grouped into five. The Rats in group A are the control, which was fed with feed and water alone. The Rats in group B were administered with Moringa oleifera only. The rats in group C were administered with Lead only. The Rats in group D were administered with Lead for the first half of the administration period, and Moringa was administered for the second half of the administration period, while the Rats in group E were administered with Lead and Moringa simultaneously, throughout the period of administration. After sixteenth day of administration, histological experiment was carried out on the blood smear and bone marrow smear, it was found out that lead has a deleterious effect on hematological parameters, as well as bone marrow and in most cases; Moringa oleifera extract reduces the severity of lead toxicity. Keywords: