Chorio-retinal thickness measurements in patients with acromegaly

Abstract

Purpose: To compare choroidal, foveal, and peripapillary retinal thickness between patients with acromegaly and healthy adults. Methods: This prospective, cross-sectional, and comparative study included 30 patients with acromegaly (study group) and 30 healthy subjects (control group). The subfoveal choroidal thickness (SFCT), foveal thickness, and peripapillary retinal nerve fibre layer thickness were measured with spectral domain optical coherence tomography. Results: The mean SFCT in the study group and in the control eyes was 374.4±98.1 and 308.6±77.3 μm, respectively (P<0.001). The mean thinnest foveal thickness value was 233.2±22.4 μm in the acromegaly group and 222.8±13.9 μm in the control group (P = 0.003). The mean peripapillary retinal nerve fibre layer thickness did not differ significantly between the groups (P = 0.34). Conclusion: The SFCT and foveal thickness were significantly higher in patients with acromegaly, whereas peripapillary retinal nerve fibre layer thickness was similar between the groups.