Deficiency of the Circulating Insulin-like Growth Factor System Associated with Inactivation of the Acid-Labile Subunit Gene

  • Domené H
  • Bengolea S
  • Martínez A
  • et al.
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Abstract

Insulin-like growth factor I (IGF-I) circulates predominantly as a 150-kD ternary complex that includes the ligand itself, IGF-binding protein 3, and an acid-labile subunit that stabilizes the comp...

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Domené, H. M., Bengolea, S. V., Martínez, A. S., Ropelato, M. G., Pennisi, P., Scaglia, P., … Jasper, H. G. (2004). Deficiency of the Circulating Insulin-like Growth Factor System Associated with Inactivation of the Acid-Labile Subunit Gene. New England Journal of Medicine, 350(6), 570–577. https://doi.org/10.1056/nejmoa013100

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