A new biphenyl from Clusia melchiorii and a new tocotrienol from C. obdeltifolia

Abstract

Chromatographic purification of the dichloromethane extract of Clusia melchiorii trunk leading to the isolation of a new biphenyl, 2,2-dimethyl-5-hydroxi-7-phenylchromene, along with the known compounds 2,2-dimethyl-5,10-dihydro-2H-benzo[g]chromene-5,10-dione (xyloidone), betulinic acid, friedelin, friedelinol, euphol, sitostenone, stigmastenone and a mixture of β-sitosterol and stigmasterol. The hexane extract of Clusia obdeltifolia trunk yielded, after chromatographic fractionation, a new δ-tocotrienilic alcohol 2Z, 6E, 10E-13-(6-hydroxy-2,8-dimethyl-3,4-dihydro-2H,2-chromenyl)-2,6, 10-trimethyl-2,6,10-tridecatrien-1-ol, along with 2Z and 2E-δ- tocotrienoloic acids, betulinic acid, betulonic acid, betunilic aldehyde, glutinol, friedelin, sitostenone and a mixture of β-sitosterol and stigmasterol. Their structures were determined from spectral data and comparison with data from previously reported compounds. ©2006 Sociedade Brasileira de Química.