Change in hospital antibiotic use and acquisition of multidrug-resistant gram-negative organisms after the onset of coronavirus disease 2019

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Abstract

Interrupted time series segmented regression was conducted to trend antibiotic use and multidrug-resistant gram-negative (MDRGN) acquisition relative to COVID-19 in an academic hospital. Total antibiotic use and antibiotic use related to pneumonia was higher in the period after the onset of COVID-19 compared to the similar calendar period in 2019. Furthermore, MDRGN acquisition increased 3% for every increase in positive COVID-19 tests per week.

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Bork, J. T., Leekha, S., Claeys, K., Seung, H., Tripoli, M., Amoroso, A., & Heil, E. L. (2021). Change in hospital antibiotic use and acquisition of multidrug-resistant gram-negative organisms after the onset of coronavirus disease 2019. Infection Control and Hospital Epidemiology, 42(9), 1115–1117. https://doi.org/10.1017/ice.2020.1360

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