Abstract
Aldoximes and ketoximes were hydroxyalkylated using (substituted) ethylene- or propylene carbonate in the presence of catalytic N-alkylated amidines or secondary amine-substituted pyridines. Thus, acetone oxime in PhMe was added over 2 h to a mixt. of ethylene carbonate and 1,8-diazabicyclo[5.4..0]undec-7-ene in refluxing PhMe and the mixt. was refluxed for a further 1 h to give 65-75% Me2C:NOCH2CH2OH.
Author supplied keywords
- 108-32-7 (Propylene carbonate)
- 1122-58-3 (4-Dimethylaminopyridine)
- 127-06-0 (Acetone oxime)
- 3001-72-7 (1,5-Diazabicyclo[4..3..0]non-5-ene)
- 5683-33-0 (2-Dimethylaminopyridine)
- 6674-22-2 (1,8-Diazabicyclo[5.4..0]undec-7-ene)
- 83495-51-6P
- 96-49-1 (Ethylene carbonate)
- ethylene carbonate oxime reaction amine catalyst
- hydroxyethyl oxime
- oxime hydroxyalkylation amine catalyst
- propylene carbonate oxime reaction amine catalyst
Cite
CITATION STYLE
APA
Blaser, D. (1995). Preparation of O-hydroxyalkylated oximes. Eur. Pat. Appl. EP: (Ciba-Geigy A.-G., Switz.).
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