Transitional cell carcinoma in orthotopic ileal neobladder 12 years after radical cystectomy

  • Hadzi-Djokic J
  • Pejcic T
  • Andrejevic V
  • et al.
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Abstract

Introduction. Some cases of secondary adenocarcinoma developing in the replaced bowel segment of urinary diversions have been reported so far. Secondary adenocarcinoma develops 20 years after surgery in about 0.5% of those in whom an ileal segment is used. There have been several reports in the literature describing extensions of transitional cell carcinoma (TCC) from the distal urether into an ileal conduit. Histology of loop tumor in 50% was TCC. The site of tumors in the majority of cases is the area at the uretheral orifices or the stoma. Case report. We presented a rare case of transitional cell carcinoma in an orthotopic ileal neobladder 12 years after radical cystoprostatectomy and ileal neobladder with the substitution by the procedure Camey II. A 65-year-old man with high-grade urothelial carcinoma of neobladder underwent partial resection of neobladder and right nephroureterectomy. Pathological analysis revealed high-grade urothelial carcinoma to the ileal neobladder (G II, Stage T2b). The patient died of laryngeal cancer a year after the surgery. Conclusion. Surgery of tumors in orthotopic neobladders is possible if diagnosed in time. In the presented case surgery resulted only in a decrease in the capacity of the neobladder without having an effect on the continence itself.Uvod. Opisani su pojedinacni slucajevi sekundarnih adenokarcinoma koji su se javili u crevnom segmentu kod urinarnih derivacija. Sekundarni adenokarcinom razvio se 20 godina posle kod oko 0.5% bolesnika kod kojih se koristi segment ileuma. Takodje, u literaturi su opisani pojedinacni slucajavi propagacije tumora iz distalnog dela uretera u ilealni konduit. Histoloski, ovi tumori su kod 50% bolesnika karcinomi prelaznog epitela. Kod najveceg broja bolesnika lokalizacija tumora je u blizini novoformiranog orificijuma. Prikaz bolesnika. Prikazali smo redak slucaj pojave karcinoma prelaznog epitela u ortotopskoj ilealnoj neobesici 12 godina nakon radikalne cistoprostatektomije. Formiranje ilealne neobesike je ucinjeno primenom postupka Camey II. Bolesniku, starom 65 godina, sa karcinomom u ilealnoj neobesici, ucinjena je desnostrana nefroureterektomija i parcijalna resekcija ortotopske ilealne neobesike. Patohistoloskom analizom utvrdjeno je da se radi o urotelnom karcinomu ilealne neobesike visokog gradusa (G II, stadijum T2b). Bolesnik je umro od laringealnog karcinoma godinu dana nakon operacije. Zakljucak. Hirurske resekcije tumora ortotopske ilealne neobesike moguce su ukoliko se tumori dijagnostikuju na vreme. Kod prikazanog bolesnika resekcija je dovela samo do snizenja kapaciteta ortotopske ilealne neobesike, bez uticaja na kontinenciju.

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APA

Hadzi-Djokic, J., Pejcic, T., Andrejevic, V., & Djurasic, L. (2013). Transitional cell carcinoma in orthotopic ileal neobladder 12 years after radical cystectomy. Vojnosanitetski Pregled, 70(11), 1062–1064. https://doi.org/10.2298/vsp1311062h

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