Immobilized Ammoniated Ruthenium Oxychloride on Functionalized Carbon Nanotubes as a Modifier for Simultaneous Determination of Biocompounds

Abstract

© 2016 The Authors. Modified glassy carbon electrode with immobilized ammoniated ruthenium oxychloride on multi-walled carbon nanotube has been used for the simultaneous determination of ascorbic acid (AA), dopamine (DA), uric acid (UA) and tryptophan (Trp). The modified electrode can well separate quaternary mixture containing AA, DA, UA and Trp from each other at 0.09, 0.323, 0.511 and 0.728 V. The measurements were performed using cyclic and liner sweeping voltammetry in a phosphate buffer solution in pH 4.0. Under optimum conditions, this modified electrode showed a linear response up to 176.8, 300.0, 310.0 and 326.0 μM with detection limits 1.5, 0.64, 0.57 and 0.61 μM for AA, DA, UA and Trp, respectively. The analytical performance of the modified electrode has been evaluated in human serum and urine samples.