COMPREHENSIVE STUDY OF CEPLUKAN FRUIT (Physalis angulata L.) USING GAS CHROMATOGRAPHY-MASS SPECTROMETRY (GC-MS)

Abstract

This study explores the potential therapeutic benefits of Ceplukan Fruit (Physalis angulata L.) and its derivatives, focusing on their secondary metabolite content. The fruit a meticulous drying process to preserve its secondary metabolites, followed by extraction and phytochemical screening to identify alkaloid compounds. Results indicate the presence of alkaloids, known for their antimicrobial and immune-stimulating properties. Further analysis via FT-IR spectroscopy reveals the functional groups present in the methanol extract, confirming the presence of carboxylic acids, aldehydes, esters, and alkanes. Additionally, GC-MS analysis identifies dominant compounds, including those with molecular formulas indicative of alkaloids, naphthalene, and azulene. Azulene and its derivatives exhibit promising pharmacological actions in dermatological therapy, such as anti-inflammatory and photoprotective effects. Overall, this study underscores the potential of Ceplukan Fruit and its derivatives in herbal medicine and dermatological treatments, highlighting the need for additional research to elucidate their mechanisms of action and ensure their safety and efficacy.