The Use of Natural Squalene and Squalane, and the Latest Situation of the Raw Materials

Abstract

For many years natural squalene has been a familiar health food supplement, while natural squalane has been the most important oily ingredient for all cosmetic products. In this paper the possibility of new application of squalene and squalane are discussed, furthermore the latest trends and the future perspective about shark liver oil which is the raw material for these compounds are described. 1 •• OE¾ •¡ "úŠe Ží ‰» •Ï •i ‹y ‚Ñ-ò-p "î ‚± ‚¤(•p)-Þ ‚Ì-û •« •¬ •ª ‚AE ‚µ ‚Ä,•L "Í ˆÍ ‚É Žg-p‚³ ‚ê ‚Ä‚¢ ‚é "V'R ƒXƒNƒAƒ‰ ƒ"‚È ‚ç ‚Ñ‚É OE'•N•H•i ‚AE‚µ‚Ä•e ‚µ ‚Ü‚ê ‚Ä‚¢ ‚é "V'R ƒXƒNƒAƒOEƒ"‚Í,‚ ‚é Ží ‚Ì ‚³ ‚ß ŠÌ-û ‚ð OE´-¿‚AE‚µ‚Ä ‚¢ ‚é •B •MŽÒ‚Í ‚± ‚ê ‚ç ‚Ìˆê‚̈ê "Ê"I •« Ž¿‹y ‚ÑOE´-¿ "®OEü‚É‚Â ‚¢ ‚ÄŠù ‚É•ñ •• ‚µ‚Ä ‚¢ ‚é ‚ª1),-{ •ñ ‚Å ‚Í ‚±‚ê ‚ç ‚Ì-p "r ‚AE•Å‹ß ‚Ì OE´-¿ Ž-•î ‚É‚Â ‚¢ ‚Ä•q ‚× ‚é. 2 ƒXƒNƒA ƒOEƒ", ƒXƒNƒAƒ‰ƒ" ‚Ì •¨-•‰»Šw"I •« Ž¿ ƒXƒNƒAƒOEƒ"‚Í,Še Ží ‚Ì "®•¨ •« ‹y ‚Ñ•A•¨ •« •H•i ‚ÉŠÜ‚Ü‚ê ‚Ä‚¢ ‚é ‚ª2),•Å ‚à '½ ‚-‚Í •[ ŠC‚É•Z ‚Þ ƒT ƒ• ‚Ì ŠÌ 'Ÿ ‚É' ¶ •Ý‚· ‚é •B 'Ò-{ "ŽŽm‚Í1916"N,‚³ ‚ß ŠÌ-û ' † ‚É' ¶ •Ý ‚· ‚é '½•s-O ˜a ‰» • ‡ •¨ ‚É ƒXƒNƒAƒOEƒ"(Squalene)‚Ì-¼‚ð-^ ‚¦ ‚½3)•B ƒc ƒmƒUƒ• ‰È(Squalidae)‚É '®‚· ‚é ƒTƒ• ‚Í,•… •[150•`1,000 m‚É • ¶ ' § ‚· ‚é "ä Šr "I •¬ OE^(•Å 'å 'Ì '·,-ñ180cm)‚Å ‚ ‚é ‚ª,ŠÌ 'Ÿ ‚ɃXƒNƒAƒOEƒ"‚ð '½-Ê ‚É •Û-L ‚µ ‚Ä‚¢ ‚é•B 'Ì •d ‚Ì-ñ1/4‚Ì ‹• 'å ‚ÈŠÌ 'Ÿ ‚Í-ñ90wt%‚ª ŠÌ-û ‚Å •è ‚ß,ŠÌ-û ' † ‚Ì ƒXƒNƒA ƒOEƒ"‚Í Žž ‚AE‚µ ‚Ä90wt%ˆÈ •ã ‚É 'B ‚· ‚é ‚à ‚Ì ‚à ‚ ‚é •B ‚Ü‚½•l ŠÔ‚Ì Še Ží Ší Š¯,'Ÿ Ší ‚É ‚à ' ¶ •Ý ‚µ,"Á ‚É •\ "ç Ž‰ Ž¿ ' † ‚É ‚Í5•`15wt%' ¶ •Ý ‚µ‚Ä ƒR ƒOE ƒXƒe ƒ• •[ ƒ‹ ‹y ‚ÑŠe Ží ƒXƒe ƒ• ƒC ƒhƒzƒ‹ ƒ‚ ƒ"‚Ì 'O‹ì 'Ì ‚AE‚µ‚Ä,•l ŠÔ‚Ì • ¶-½ˆÛŽ• ‚É•d-v‚È-ð Š" ‚ð ‰Ê ‚½ ‚µ‚Ä ‚¢ ‚é4). ƒXƒNƒA ƒOE ƒ"(2,6,10,15,19,23-ƒw ƒLƒT ƒ• ƒ` ƒ‹ •[2,6, 10,14,18,22ˆê ƒe ƒgƒ‰ ƒRƒTƒwƒLƒTƒGƒ")‚Í,6OE ‚Ì "ñ ‹¤-ð "ñ •d OE‹• ‡ ‚ð-L‚µ ‚½ƒC ƒ\ ƒv ƒOEƒmƒC ƒhOEn'Y‰»•…'f ‰» • ‡ •¨ ‚Å,(1)‚Ì •\ '¢ ‚ð Ž• ‚¿,•ª ŽqŽ®C30H50,•ª Žq-Ê410.7‚Å ‚ ‚é. (1) ƒXƒNƒAƒOE ƒ"‚Ì •¸ •» •i ‚Í,-³ •L‚È‚¢ ‚µ‚í ‚¸‚©‚ɉõ‚¸‚©‚ɉõ ‚¢ ‚É‚¨ ‚¢ ‚Ì ‚· ‚é-³ •F" §-¾-û•« ‰t 'Ì ‚Å,•… ‚É ‚Í ‚Ù‚AE ‚ñ ‚Ç-n ‚¯ ‚¸, ƒG•[ ƒeƒ‹,•Î-û•H-ƒe ƒ‹,ƒx ƒ"ƒ[ ƒ",ƒN ƒ• ƒ•ƒzƒ‹ ƒ€"™‚É ‚Í-e ˆÕ‚É-n ‰ð ‚· ‚é•B ƒAƒ‹ ƒR•[ ƒ‹,•X •| Ž_‚É‚Í ‚í ‚¸‚©‚É‚¸‚©‚É ‚µ ‚©-n ‚¯ ‚È‚¢ •B•\ ˆê1‚É ‚» ‚Ì •¨-• ‰» Šw"I •« Ž¿‚𠎦 ‚µ‚½. ƒXƒN ƒAƒOE ƒ"‚Í,'½ •s-O˜a ‰» • ‡ •¨ ‚È‚Ì ‚ʼn» Šw"I ‚É•s ˆÀ'è ‚Å,‹ó ‹C ‚É•G‚ê ‚é ‚AE Ž_‰» ‚³ ‚ê‰ß Ž_‰» •¨ ‚ð •ì ‚è‚â ‚· ‚-,'… •F ‚µ‚½‚è,"S ‚¿ ‚å ‚¤‚É‚È ‚Á‚½‚è,•s ‰õ •L‚ð "-‚· ‚é ‚± ‚AE ‚ª ‚ ‚é•BŽ_‰»-hŽ~•Ü‚AE‚µ‚Ä‚Í,ƒr ƒ^ ƒ~ƒ"•[E,BHT‚È ‚Ç‚ª-L OEø ‚Å‚ ‚é. ƒXƒNƒAƒ‰ ƒ"(2,6,10,15,19,23-ƒw ƒLƒTƒ• ƒ`ƒ‹ ƒe ƒgƒ‰ ƒRƒTƒ")‚Í,‰» Šw"I ‚É•s ˆÀ'è ‚È ƒXƒNƒAƒOE ƒ"‚ðNiOEn •G"} ‚È‚Ç‚ð-p ‚¢‚Ä,Š® 'S ‚É•… 'f "Y‰Á ‚µ‚½(2)‚Å Ž¦ ‚³ ‚ê ‚é-O˜a 'Y‰» •… 'f ‰» • ‡ •¨ ‚Å,•ª ŽqŽ®C30H62,•ª Žq-Ê422.8‚Å ‚ ‚é.