Bioassay of captan by zebrafish larvae [20]

Abstract

CAPTAN (N-trichloromethylthio-4-cyclohexene-1,2-dicarboxyimide) is an agricultural fungicide of low mammalian toxicity, and its residues*; in agricultural products are considered to offer less risk than most pesticides. A recent report1 draws attention to the mutagenic and teratogenic properties of captan, which has been observed to increase the mutation rate in bacteria (Escherichia coli), to inhibit mitotic division in the cell cultures and to induce physical abnormalities in chicks treated in the embryonic stage. © 1967 Nature Publishing Group.