A Study on Renal Function Tests and its Correlation with Blood Glucose and eGFR in Newly Diagnosed Type 2 Diabetes Mellitus

Abstract

Background and Objectives: Diabetes mellitus is a metabolic disorder characterized by increased blood sugar levels. It is of two types. Type two is very common, due to deficiency in secretion of insulin. That eventually affects derangement of carbohydrate, protein and lipid metabolism. On long standing, this metabolic derangement will affect vital organs like liver, kidney, brain etc. To study correlation analysis that determine strength and direction of relationship between indicator of DM (FBS and PPBS) and RFT (serum urea and serum creatinine) in Indian population. Methods: A retrospective study design was done in government hospital, Rajkot, Gujarat, India (study population).Total 1,45,369 patients in period of April 2023 to April 2024 included in this study .Data sources from the laboratory tests. The patients who were tested for RFT (serum urea and serum creatinine) and DM (Plasma FBS, Plasma PPBS) were included in this study. Results: A total of 1,45,369 cases were studied from April 2023 to April 2024 (1 year) of which 64% of males and 36% were females. Based on statically significant variables, multiple binary logistic using stepwise regression analysis was performed to determine that direct association of renal function test with diabetes mellitus. Conclusions: Long standing diabetes can affect multisystem like neuropathy, nephropathy. Therefore, regular monitoring of RFT is essential in diabetic patients.