Rotación de antimicrobianos en la Unidad de Terapia Intensiva: ¿Es ésta una estrategia útil?

Abstract

Antimicrobial resistance is a significant problem in the Intensive Care Unit related to increased morbidity, mortality and represents more costs in these facilities. Cycling of antibiotics is a new tool against bacterial resistance. In medical literature there is evidence of its benefits in lowering the emergence of resistant strains but clinical experience is still scarce and its implementation implies a profound change in guidelines and hospital policies that compromises the participation of all medical staff.