Obesity and Diabetes

Abstract

Weight reduction strategies are part of the basic therapy for people with obesity or type 2 diabetes. People with type 2 diabetes should be motivated to eat a healthy and balanced diet and increase physical activity. Targeted weight reduction is also an escalation step in therapy for patients with type 2 diabetes. When choosing drug therapy for type 2 diabetes, preference should be given to active ingredients (metformin, GLP-1 receptor agonists, SGLT2 inhibitors) that enable weight reduction. Since weight reduction for people with obesity or type 2 diabetes is difficult to achieve through conservative therapeutic strategies, metabolic surgery has developed into the therapy alternative for patients with type 2 diabetes and a BMI > 35 kg/m2 in recent years. Compared to conservative type 2 diabetes therapy, metabolic surgery is significantly more effective in terms of weight reduction, long-term weight stability and blood glucose reduction, but is also associated with higher acute and long-term risks.