Evaluation of antioxidant and anti-mutagenic activity of naturally fortified honey with curcuma longa extract

Abstract

The current research planned to explore the activity to anti-mutagenic and anti-oxidant to naturally fortified honey with Curcuma longa extract. The fortified honey was evaluated by GC MASS method. The activity of the anti-oxidant elevated due to the activity of the free radicals in 1, 1-Diphenyl-2-picryl-hydrazyl (DPPH), nitric and super oxide. Scavenge is achieved by alkaline DMSO and lipid per oxidation method, While anti mutagenic activity were assessed by mitotic index (MI), chromosomal aberration (CA) and Micronuclei (MN,) tests. The outcomes data from the current work shows fortified honey had a highest antioxidant activity in compare with Curcuma longa extract .Results of genotoxic activity showed that furfural increased formations of MNs, CA and MI in blood culture associated with control, opposing, fortified honey by itself didn't display any effect in geno-toxic while the effect in anti-mutagenic of honey could be related the capability of scavenge power to antioxidant for free radical.