Prevalence of thrombocytopenia during pregnancy, and its effect on pregnancy and perinatal outcome

Abstract

Background: To study the prevalence of thrombocytopenia during pregnancy, its etiology and maternal and perinatal outcome. Methods: It was a prospective one year study of pregnancy with thrombocytopenia. The prevalence and cause of thrombocytopenia during pregnancy and its effect on maternal and perinatal outcome was studied. Result: Among 990 deliveries, 104 women were having thrombocytopenia during pregnancy. The commonest etiology was gestational thrombocytopenia (61.53%). Fetal complications were still birth (5.88%), low birth weight (14.7%), and neonatal thrombocytopenia (1.92%). Thrombocytopenia in pregnancy did not affect the mode of delivery and pre-term delivery rate. Conclusion: Gestational thrombocytopenia, preeclampsia, HELLP syndrome, malaria, ITP and dengue were the common causes of thrombocytopenia in pregnancy. Patients with GT and ITP have better maternal and perinatal outcomes as compared to preeclampsia and HELLP syndrome.