An efficient one pot synthesis and antimicrobial activity of novel S-alkylisothiosemicarbazone and imidazolidinone derivatives of pyrazole carbaldehyde

Abstract

S-Alkylisothiosemicarbazone and imidazolidinone derivatives were synthesised from pyrazole 4-carbaldehyde in a one pot reaction. The synthesised compounds were characterized by IR, 1H NMR, 13C NMR, mass and elemental analysis. Most of the synthesised compounds showed antimicrobial activity against S. Aureus, B. subtilis, E. coli, P. aeruginos, A. Niger and C. albicans.