RCMV increases intimal hyperplasia by inducing inflammation, MCP-1 expression and recruitment of adventitial cells to intima

  • Grudzinska M
  • Bojakowski K
  • Soin J
  • et al.
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Abstract

Cytomegalovirus (CMV) infection has been associated with accelerated transplant vasculopathy. In this study, we assessed the effects of acute rat CMV (RCMV) infection on vessel remodeling in transplant vasculopathy, focusing on allograft morphology, inflammation and contribution of adventitial cells to intimal hyperplasia.

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Grudzinska, M. K., Bojakowski, K., Soin, J., Stassen, F., Söderberg-Nauclér, C., & Religa, P. (2010). RCMV increases intimal hyperplasia by inducing inflammation, MCP-1 expression and recruitment of adventitial cells to intima. Herpesviridae, 1(1), 7. https://doi.org/10.1186/2042-4280-1-7

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