Abstract
A 60-year-old woman with stage IV rectal cancer received adoptive cell therapy with autologous cancer antigen (AC-ACT) causing induction of anti-oncogenic and anti-PD-L1 miRNAs as assessed by miRNA microarray. More than 1 year after AC-ACT, metastases have been arrested, and the patient reports good quality of life.
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Chinami, M., Iwabuchi, K., Muto, Y., Uchida, Y., Arita, R., Shuraim, R. A., & Adra, C. N. (2019). Assessment by miRNA microarray of an autologous cancer antigen-pulsed adoptive immune ensemble cell therapy (AC-ACT) approach; demonstrated induction of anti-oncogenic and anti-PD-L1 miRNAs. Clinical Case Reports, 7(11), 2156–2164. https://doi.org/10.1002/ccr3.2343
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