Molecular and biochemical pharmacology of the histamine H 4 receptor

Abstract

The elucidation of the human genome has had a major impact on histamine receptor research. The identification of the human H 4 receptor by several groups has been instrumental for a new appreciation of the role of histamine in the modulation of immune function. In this review, we summarize the historical developments and the molecular and biochemical pharmacology of the H 4 receptor. © 2009 The British Pharmacological Society All rights reserved.