Identification of the components by lcms/ms-qtof and toxicity of ethanol extracts of musa paradisiaca l. Stems

Abstract

Banana plants from the Musaceae family thrive in tropical countries, especially in Indonesia, with various types and one of them is Musa paradisiaca Linn (MPL). Banana is an important horticultural plant considering its high productivity and take place regardless the season. Various parts of banana plants such as flower, fruit, leave, stem, and tuber can be utilized as food. Chemical constituents of ethanol extract of MPL stem were identified and characterized by LCMS/MS-QTOF. Based on the results of MS fragmentation, MPL extracts contained 10 components which were Mubenoside A; 25 (R)-Ruscogenin-1-O-β-D-glucopyranosyl (1 → 2)-β-D-fucopyranoside; Oleanolic acid 3-O-β-D-xylopyranosyl-(1 → 2)-α-L-arabinopyranosyl-28-O-β-D glucopyranosyl-(1 → 6)-β-D glucopyranoside; Raddeanoside; Baicalein-6-glucuronide; Undulatoside A; 26-Deoxyactein; Methyl ophiopogonone A; Ginsenoside Rh4; Eclalbasaponin VIII. These constituents were found to be compounds with known medicinal activity. A toxicity test was performed by Brine shrimp lethality bioassay. The toxicity properties of ethanol extract of MPL showed LC50 894.46 ppm.