Increased Levels of Lipid Oxidation Products in Rheumatically Destructed Bones of Patients Suffering from Rheumatoid Arthritis

Abstract

Hydroxy Fatty Acids, Epoxy Fatty Acids, Rheumatoid Arthritis, Bones The new indicator for lipid peroxidation (LPO) processes - 9-hydroxy-10,12-octadecadienoic acid (9-HODE) - was used to investigate, whether LPO processes are increased in destructed bone material of patients suffering from rheumatoid arthritis (RA) in comparison to surrounded non destructed bone material. The HODE content in destructed bones exceeded that of non destructed ones of the same patient for a factor of about 3. © 1998, Verlag der Zeitschrift für Naturforschung. All rights reserved.