Pyridazino‐1,3a,6a‐triazapentalenes as versatile fluorescent probes: Impact of their post‐functionalization and application for cellular imaging

Abstract

Pyridazino‐1,3a,6a‐triazapentalenes (PyTAP) are compact fused 6/5/5 tricyclic scaffolds which exhibit promising fluorescent properties. Chemically stable, they can be post‐functionalized using standard Pd‐catalyzed cross‐coupling chemistry. Several original PyTAP bearing additional unsaturated substituents in positions 2 and 8 were synthetized and their spectroscopic properties analyzed. They have been successfully tested as fluorescent probes for cellular imaging.