LINking microRNAs, kidney development, and Wilms tumors

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Abstract

In this issue of Genes & Development, Urbach and colleagues (pp. 971-982) provide compelling data suggesting a role for LIN28 in the pathogenesis of a significant percentage of Wilms tumors. These data extend our insights in the genetics underlying Wilms tumor development and emphasize the importance of stemness and microRNAmediated processes in the origins of these tumors. © 2014 Hohenstein and Hastie.

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Hohenstein, P., & Hastie, N. D. (2014). LINking microRNAs, kidney development, and Wilms tumors. Genes and Development, 28(9), 923–925. https://doi.org/10.1101/gad.242735.114

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