Description of a possible clonal expansion of Plasmodium vivax in Manaus-Amazonas-Brazil.

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Abstract

Atypical P. vivax cases reported in Manaus municipality led us to detect a genetic isolate of P. vivax. Variable regions of SSUrRNA were examined from the initial time of infection and in the two recrudescences/relapses from a patient exhibiting chloroquine and primaquine resistance. A unique isolate, found at all stages of infection, suggests the presence of a clonal expansion.

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Alecrim, M. dos G., Alecrim, W. D., Macêdo, V., Korves, C. T., Roberts, D. R., Li, J., … McCutchan, T. F. (1999). Description of a possible clonal expansion of Plasmodium vivax in Manaus-Amazonas-Brazil. Revista Da Sociedade Brasileira de Medicina Tropical, 32(3), 303–305. https://doi.org/10.1590/S0037-86821999000300014

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