Atypical Manifestations of IgG4-Related Disease as Multiple Liver Abscesses with Subcapsular Tracts and Migratory Pulmonary Nodules Mimicking Parasitic Infection

Abstract

Immunoglobulin G4-related disease (IgG4-RD) is a fibroinflammatory condition that becomes more recognized as multi-systemic disorders, characterized by three histological hallmarks of IgG4-positive lymphoplasmacytic tissue infiltrate, storiform fibrosis, and obliterative phlebitis. This disease has been reported in virtually every organ system, but the hepatic manifestations remain poorly defined. Moreover, IgG4-RD can mimic many malignancies, inflammatory disorders and infectious diseases. This report revealed IgG4-related liver disease with atypical presentation presenting with multiple liver abscesses and linear tracts mimicking parasitic infection.