Clearance of mycoplasma genitalium and trichomonas vaginalis among adolescents and young adults with pelvic inflammatory disease: Results from the tech-N study

Abstract

Current pelvic inflammatory disease (PID) treatment effectively treats Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT). However, coverage may be inadequate for Mycoplasma genitalium (MG)/ Trichomonas vaginalis (TV) infections. We compared the longitudinal MG and TVoutcomes with NG/CToutcomes for women enrolled in a longitudinal randomized controlled trial to optimize outcomes after PID. The prevalences of CT and NG were lower at 30- and 90-day follow-up compared with the prevalence at the time of diagnosis.No significant difference was observed for MG (odds ratio, 0.95; 0.86-1.04; P = 0.265) and TV (odds ratio, 0.89; 0.75-1.04; P = 0.146) over time for both treatment groups, showing that persistence and/or reinfection with MG and TVoccurs more frequently than with CTor NG after treatment of PID using current national treatment guidelines.