Bilateral lesions of the globus pallidus in a young woman

Abstract

We report a case of stroke due to cocaine abuse in a 30-year-old woman. The initial examinations pointing to this diagnosis were CT and MRI. Magnetic Resonance Imaging revealed bilateral globus pallidus infarction characterized by restricted Diffusion with low ADC values. There was also a partial hemorrhagic component confirmed on T2* sequence. After gadolinium injection there was a ring enhancement consistent with a blood brain barrier leakage. Similar lesions have been described in post hypoxic-anoxic injuries such as following cardiac arrest, severe blood loss and CO intoxication.