The Effect of Statins on Type II Diabetes Mellitus

Abstract

Background: GBP is known to control type 2 diabetes. The question has often been raised as to whether the effect is temporal or a cure. This study on the long term effect of GBP on type II diabetes was undertaken to answer the question. Methods: A retrospective review of the records of all patients who had the BGBP at the Center for Surgical Treatment of Obesity between 1993 and 1995 with a diagnosis of diabetes were reviewed. The immediate and long term outcomes were extracted and analyzed and will be presented. Result: 683 patients had BGBP between1993-95. 72(8 {%}) had a diagnosis of type II diabetes mellitus. Of these, 20(28{%}) were insulin dependent, 29(40{%}) were on oral anti diabetic agents and 25(32{%}) were recent onset diabetics. All patients were discharged home on no medications. Within two weeks of discharge 58(80{%}) were euglycemic and 14(20{%}) were replaced on lower doses of insulin and/or oral antidiabetic agents. At ten years, of the 41(57{%}) patients that were available for follow up, 34(83{%}) were cured. One was on low dose of insulin and six were on oral antidiabetic agents. Conclusion: The 80{%} remission rate seen within two weeks of GBP is maintained at ten years of follow up. It does appear that BGBP produces a long term remission or a cure in morbidly obese patients with type II diabetes mellitus.