Automated radiography assessment of ankle joint instability using deep learning

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Abstract

This study developed and evaluated a deep learning (DL)-based system for automatically measuring talar tilt and anterior talar translation on weight-bearing ankle radiographs, which are key parameters in diagnosing ankle joint instability. The system was trained and tested using a dataset comprising of 1,452 anteroposterior radiographs (mean age ± standard deviation [SD]: 43.70 ± 22.60 years; age range: 6–87 years; males: 733, females: 719) and 2,984 lateral radiographs (mean age ± SD: 44.37 ± 22.72 years; age range: 6–92 years; male: 1,533, female: 1,451) from a total of 4,000 patients, provided by the National Information Society Agency. Patients who underwent joint fusion, bone grafting, or joint replacement were excluded. Statistical analyses, including correlation coefficient analysis and Bland-Altman plots, were conducted to assess the agreement and consistency between the DL-calculated and clinician-assessed measurements. The system demonstrated high accuracy, with strong correlations for talar tilt (Pearson correlation coefficient [r] = 0.798 (p

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Noh, S., Lee, M. S., & Lee, B. D. (2025). Automated radiography assessment of ankle joint instability using deep learning. Scientific Reports, 15(1). https://doi.org/10.1038/s41598-025-99620-6

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