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Reduction of bacterial titers by low-dose aspirin in experimental aortic valve endocarditis

Infection and Immunity
DOI: 10.1128/iai.61.4.1593-1595.1993
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Abstract

Using a rabbit model of Staphylococcus aureus endocarditis, we studied the effects of aspirin on the natural progression of this infection. Compared with untreated animals, the aspirin-treated animals showed a 30% (P = 0.11) reduction in the weight of the vegetations and an 84% (P = 0.03) reduction in the bacterial titer of the vegetations.

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Nicolau, D. P., Freeman, C. D., Nightingale, C. H., Quintiliani, R., Coe, C. J., Maderazo, E. G., & Cooper, B. W. (1993). Reduction of bacterial titers by low-dose aspirin in experimental aortic valve endocarditis. Infection and Immunity. https://doi.org/10.1128/iai.61.4.1593-1595.1993

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