Delay of cell growth and loss of stemness by inhibition of reverse transcription in human mesenchymal stem cells derived from dental tissue

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Abstract

The present study investigated the cellular properties in the dental tissue-derived mesenchymal stem cells (DSCs) exposed to nevirapine (NVP), an inhibitor of reverse transcriptase (RTase). After a prolonged exposure of DSCs for 2 weeks, the population doubling time (PDT) was significantly (P

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Lee, W. C., Kim, D. Y., Kim, M. J., Lee, H. J., Bharti, D., Lee, S. H., … Jeon, B. G. (2019). Delay of cell growth and loss of stemness by inhibition of reverse transcription in human mesenchymal stem cells derived from dental tissue. Animal Cells and Systems, 23(5), 335–345. https://doi.org/10.1080/19768354.2019.1651767

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