Patent

Hydroxyazepanes as inhibitors of glycosidase and HIV protease

  • Wong C
  • Moris-Varas F
(1998), AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU
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Abstract

Hydroxyazepanes display inhibitory activity with respect to glycosidase, with Ki values from moderate to low micromolar range. Benzyl and 3,6-dibenzyl derivs. of hydroxyazepanes display inhibitory activity with respect to HIV protease. These compds. are synthesized either by chemoenzymic or chem. methodologies

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Wong, C. H., & Moris-Varas, F. (1998). Hydroxyazepanes as inhibitors of glycosidase and HIV protease. PCT Int.Appl.WO 9837218 A1 27 Aug 1998. The Scripps Research Institute, USA.

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