RefProtDom: A protein database with improved domain boundaries and homology relationships

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Abstract

Summary: RefProtDom provides a set of divergent query domains, originally selected from Pfam, and full-length proteins containing their homologous domains, with diverse architectures, for evaluating pair-wise and iterative sequence similarity searches. Pfam homology and domain boundary annotations in the target library were supplemented using local and semi-global searches, PSI-BLAST searches, and SCOP and CATH classifications.

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Gonzalez, M. W., Pearson, W. R., & Frishman, D. (2011). RefProtDom: A protein database with improved domain boundaries and homology relationships. In Bioinformatics (Vol. 27, pp. 2361–2362). Oxford University Press. https://doi.org/10.1093/bioinformatics/btq426

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