Chemical characterization of Chlamydia trachomatis lipopolysaccharide

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Abstract

The group-specific antigen of Chlamydia trachomatis serotype L2 was chemically analyzed. It is composed of typical lipopolysaccharide (LPS) components, i.e., D-glucosamine, long-chain 3-hydroxy fatty acids, 2-keto-3-deoxyoctonic acid, and phosphate in a molar ratio of approximately 2:5:3:2.6, respectively, resembling enterobacterial LPS of the Re chemotype. For the first time, 3-hydroxydocosanoic acid (3-OH C22:0) was found as an LPS constituent.

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Nurminen, M., Rietschel, E. T., & Brade, H. (1985). Chemical characterization of Chlamydia trachomatis lipopolysaccharide. Infection and Immunity, 48(2), 573–575. https://doi.org/10.1128/iai.48.2.573-575.1985

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