Treatment of Feline panleukopenia Virus Infection in Naturally Infected Cats and its Assessment

Abstract

Background and Objective: High mortalities recorded in diseased cats with Feline panleukopenia virus infection (FPV) and failure of treatment in most of those cases has stimulated us to evaluate different types of treatment used to treat cat with Feline panleukopenia viral infection (FPV) in different ages. Material(s) and Method(s): About 300 cats showing signs suggestive for (FPV) infection were subjected to clinical examination, Rapid enzyme-linked immunosorbent assay (ELISA) on fecal sample to detect viral antigen and blood examination complete blood picture (CBC). Clinical examination revealed the presence of fever, depression, vomiting, diarrhea and dehydration. ELISA on fecal samples was positive for FPV in all the 300 examined cats. Panleukopenia was detected in the examined blood samples. A trail for treatment was applied using supportive classical treatment for all of the diseased cats while 2 groups (each of 100 cats) received also Feliserine Plus and Zylexis as trail for treatment using antibodies specific against FPV and as a source for interferon to control viral infection Results: Recovery rate in the form of clinical improvement and survival of diseased animals were significantly higher in the group treated by Feliserine Plus (85%) followed by the group treated by Zylexis (16.%) in age groups of 6-7, 8-10,12 and 24 months, while sex has no effect using chi-square test. Conclusion(s): The use of Feline specific neutralizing antibodies against FPV proved to be more efficient in treatment of diseased cats in comparison to the use of inactivated parapox ovis strain D1701, while the use of supportive and classical treatment only gave the lower recovery and survival rate among diseased cats.Copyright © 2019 Romane Adieb Awad et al.