Four new meroterpenes, guignardones F-I (1-4), together with two known compounds guignardones A (5) and B (6 ) were isolated from the endophytic fungus A1 of the mangrove plant Scyphiphora hydrophyllacea. Their structures and relative configurations were elucidated by spectroscopic data and single-crystal X-ray crystallography. A possible biogenetic pathway of compounds 1-6 was also proposed. All compounds were evaluated for inhibitory activity against methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus aureus. © 2012 by the authors; licensee MDPI.
CITATION STYLE
Mei, W. L., Zheng, B., Zhao, Y. X., Zhong, H. M., Chen, X. L. W., Zeng, Y. B., … Dai, H. F. (2012). Meroterpenes from endophytic fungus A1 of mangrove plant Scyphiphora hydrophyllacea. Marine Drugs, 10(9), 1993–2001. https://doi.org/10.3390/md10091993
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