Fabrication of Bio-friendly Polymer Nanosheets for Biomedical Applications

Abstract

We have developed self-standing bio-friendly nanosheets for biomedical applications. These nanosheets were fabricated by simple processes of spin-coating and a novel peeling technique from the substrate. Centimeter-sized nanosheets have unique properties such as amazingly flexibility and high adhesiveness. They could act as a novel wound dressing instead of conventional suturing in surgery. By contrast, fragmented submillimeter-sized nanosheets could act as aqueous surface modifiers to coat even uneven and irregular surfaces in addition to flat surfaces. In fact, such fragmented nanosheets exhibited a high potential to protect burned skin from bacterial infection and to provide blood compatibility to several surfaces. These nanobiomaterials therefore constitute a promising alternative to conventional therapies and coatings in biomedical fields.